Mary Jane De Souza

 Mary Jane De Souza

Professor of Kinesiology and Physiology

Contact Information

104 Noll Laboratory
The Pennsylvania State University
University Park PA 16802


(fax) 814-865-4602



Ph.D., 1988, Exercise Physiology, University of Connecticut

Research Interests

Women's health and physical activity, Female Athlete Triad (low energy availability with or without disordered eating, amenorrhea and osteoporosis), effects of exercise on the menstrual cycle, eating behaviors and food intake, bone health and osteoporosis in female athletes, and energy deficiency and bone health


  • Etiology of and treatment of the Female Athlete Triad
  • Skeletal health in exercising women and athletes
  • Reproductive endocrinology of menstrual disorders in exercising women
  • RCTs of increased food intake in Triad-affected exercising women

Selected Publications

MacNutt, M. De Souza MJ, Tomczak S, Homer J, Sheel A. Resting and exercise ventilatory chemosensitivity across the menstrual cycle. Journal of Applied Physiology. 2012, 112(5):737-747, Dec 15. [Epub ahead of print].

Hill BR, De Souza MJ, Williams NI. Characterization of the Diurnal Rhythm of Peptide YY and its Association with Energy Balance Parameters in Normal Weight Premenopausal Women. American Journal of Physiology: Endocrinology and Metabolism. 2011, 1 Aug;301(2):E409-15. Epub 2011 May 24.

Scheid JL, De Souza MJ, Leidy HJ, and NI Williams. Ghrelin but not PYY is related to body weight and energy availability. Medicine & Science in Sports & Exercise. 2011,43(11):2063-71.

Scheid JL, Toombs RJ, Gibbs JC, Ducher, G, Williams NI, De Souza MJ. Estrogen and Peptide YY are associated with bone mineral density in premenopausal exercising women. Bone. 2011 Aug;49(2):194-201. Epub 2011 Apr 28.

De Souza, MJ. JL Scheid, RJ Toombs, M Corr, JC Gibbs, SA Awdishu, S Laredo, NI Williams. Reproductive Profiles, Androgen Hormones and Energetic Status of Oligomenorrheic Exercising Women. Journal of Applied Physiology. In Review. 2011.

Gibbs JC, Williams NI, Scheid JL, Toombs RJ, De Souza MJ. A high drive for thinness is associated with energy deficiency and severe menstrual disturbances: Confirmation in a large population of exercising women. International Journal of Sports Nutrition and Exercise Metabolism. 2011 Aug;21(4):280-90.

Strategic Themes

  • Domains of Health and Behavior
  • Populations of Special Interest