Jennifer E. Graham-Engeland

• Stress and health
• Affect (emotion) and health
• Inflammation
• Chronic pain
• Individual differences (particularly related to gender and age)

Detailed Research Interests

Jennifer Graham-Engeland investigates the impact of psychological stress on physical health and the psychological, physiological and behavioral mechanisms underlying stress and health connections. She emphasizes the impact of cognitive and emotional responses to stress (e.g., rumination, meaning-making, anger) that are potential targets for non-pharmacological intervention. Drawing on perspectives from social psychology and psychoneuroimmunology, specific topics include: 1) adaptive consequences of recognizing and expressing negative emotion; 2) how emotion, depressed mood, inflammation, and physical pain are bi-directionally connected; 3) the use of immune-related biomarkers (particularly inflammatory markers) as outcomes or mediators of stress and health phenomena, and 4) the relevance of situational forces (e.g., relationship dynamics) and individual differences (e.g., hostility, loneliness, and gender) on stress and health connections. For more information, see The Stress and Health Lab web pages.

Dr. Jennifer Graham-Engeland joined the Biobehavioral Health faculty at Penn State in 2006. She is now the Professor-in-Charge of the Graduate Program in Biobehavioral Health. Dr. Graham-Engeland also serves on the editorial board for the journal Annals of Behavioral Medicine and Health Psychology Review, and is a standing member of the NIH study section “Social Psychology, Personality, and Interpersonal Processes (SPIP)”. In addition, Dr. Graham-Engeland is also a dedicated instructor; she has taught multiple graduate and undergraduate courses, including Integrative Integration in Biobehavioral Health, Gender and Health, and Professional Development for graduate students.

Inflammatory Mediators of Stress and Cognitive Aging

NIH R01 AG042595-01   Graham-Engeland  & Engeland (PI) 

10/2012 - 10/2017,  NCE

National Institute on Aging (NIA), with National Institute on Mental Health (NIMH)
This project is investigating the degree to which inflammation mediates associations between psychological stress, rumination, and indicators of cognitive ability over time among midlife adults.

Role: Multiple PI (MPI; with MPI Christopher Engeland)

Integrative Biobehavioral and Psychosocial Risk for Cognitive Decline in the Elderly

NIH R01 AG056487-01  Engeland & Graham-Engeland (PI)         

07/01/2018 - 04/30/2023                                       

National Institute on Aging (NIA)

The major goals of this project are to investigate the role of three interactive factors – negative and positive affect, inflammation, and lipid profiles – on cognitive aging outcomes, and the impact of cumulative lifetime stress on associations between affect and inflammation with cognition.

Role:  Multiple PI (MPI; with MPI Christopher Engeland)

Early Psychosocial Intervention and Child and Parent Cardiovascular Disease Risk

NIH R01 12255789   Schreier (PI)                                     

01/15/2018-01/14/2023

National Heart, Lung, and Blood Institute (NHLBI)

This project builds on the Family Foundations (FF) intervention, an ongoing NICHD-funded (PI: Feinberg, HD058529) randomized controlled trial, to determine effects of a perinatal coparenting-focused intervention on both child and parent inflammatory markers and other biomarkers of CVD risk.

Role: Co-Investigator

Sex hormones, inflammation, and cognitive decline in older men and women

NIA R21 AG066140 (Knight (PI)

09/15/2019 - 09/14/2021

This project builds on the Einstein Aging Study (EAS) to determine whether sex hormones protect against cognitive decline via suppressive effects on inflammation

Role: Co-Investigator

For more information about current projects and recent publications, see the Stress and Health Lab web pages