Christopher G. Engeland

• Effects of stress, age, and sex on wound healing and inflammation (human, animal)
• Stress, inflammation, cognitive aging, and dementia (human)
• Inflammatory biomarkers and stress as predictors of preterm birth (human)
• Inflammation and depression (human)

Honors

• 2021: Janet Williamson Award for Excellence in Training (Nursing)
• 2016: Journal of Midwifery & Women's Health Best Research Article of the Year
• 2013: Faculty Scholarship Award (Research)
• 2004: 1st Place Postdoctoral Research
• 2004, 2005: PNIRS Research Scholars Award
• 1999, 2000, 2001: Accuscan SFN Research Award
• 2000, 2001, 2002: IBNS Research Scholars Award
• 1999-2001: Ontario Graduate Scholarship in Science and Technology
• 1999-2002: Ontario Graduate Scholarship

How factors such as stress, age, gender, and hormones affect immunity, inflammation, and health. I am particularly interested in tissue repair (mucosal and dermal wound healing). Also the feasibility of biomarkers for predicting health outcomes. I conduct both human and animal research.

Current Funded Research Projects

• Einstein Aging Study 04/01/2022-03/31/2028
  • 1) P01 - Project Leader (Engeland, Graham-Engeland), Depression, inflammation, biological age, and cognitive function, Role: Project Leader (multiple)
  • 2) P01 - Core Leader (Engeland, Pavlovic), Biomarker Core, Role: Core Leader (multiple)
• Stress, racism, and cardiovascular risk among urban African American adults: A multilevel, mixed methods approach 04/01/2021-03/31/2026, Role: Co-I (PI at Penn State)
• Psychosocial and neighborhood mechanisms and consequences of Black-White sleep disparities on cognition 08/15/2021-07/31/2026, Role: Co-I
• The role of loneliness in cognitive decline and risk for dementia 04/01/2023-03/31/2025, Role: Co-I
• Prospective memory in everyday life: Lapses and decline in relation to inflammatory and neurodegenerative biomarkers in older adults 05/15/2023-11/30/205, Role: Consultant
• Stress and affective mechanisms that relate to inflammation in diverse older men and women 09/15/2024-08/31/2026, Role: Consultant
• Global collaborative research on establishing a Korean older adult cohort 05/01/2024-05/01/2027, Role: Consultant
• The Geroscience and Dementia Prevention Consortium – Penn State (Paul), A scalable patient to petri dish (P2P) initiative for investigating Alzheimer’s Disease, Role: Co-I

Previous Funded Research Projects

• Examining within-person differences in the simultaneous quantification of Epstein-Barr virus, Cytomegalovirus, and Human Herpesvirus-6 in fasting and non-fasting bloods 01/01/2025-06/30/2025, Role: PI
• Integrative biobehavioral and psychosocial risk for cognitive decline in the elderly (Engeland, Graham-Engeland) 07/01/2018-3/31/2023, Role: PI (multiple)
• Sex hormones, inflammation, and cognitive decline in older men and women 09/15/2019-05/31/2022, Role: PI (multiple)
• Social stressors and inflammations: A mixed methods approach to preterm birth 01/06/2017-07/31/2022, Role: Co-I (PI at Penn State)
• Elucidating the necessary components and mechanisms of cognitive training (ENACT) 09/30/2018-05/31/2021, Role: Co-I
• A non-pharmacological multi-modal therapy to improve sleep and cognition and reduce mild cognitive impairment risk 06/01/2020-05/31/2022, Role: Co-I
• Neural, Inflammatory and Behavioral Markers of Anhedonia in Treatment Resistant Depression 09/01/2019-08/31/2021, Role: Co-I
• A neurobiological model of anticipatory anhedonia: The association of inflammation and reward circuitry dysfunction in treatment resistant depression 06/01/2020-06/30/2023, Role: Faculty Mentor/ Co-I
• Brain-gut-genome profiling in connective tissue disorder-related gastrointestinal dysfunction 06/01/2022-05/31/2024, Role: Consultant
• CTSI Bridges to Translation Award (Engeland) 11/01/2015 – 12/31/2016 $45,980 Penn State University. Hyperglycemia and impaired healing in medically complex surgical patients. Role: PI
• Inflammatory Mediators of Stress and Cognitive Aging. NIH (R01AG042595), 2012-2017. C. Engeland (MPI), J. Graham (MPI).
• Feasibility of a Stress Reduction Intervention Study in Sickle Cell Disease. UIC Midwest Roybal Center for Health Promotion and Translation, 2014-2015. C. Engeland (Co-I).
• Healthy Aging in a Changing Climate: Heat Wave Survival, Critical Biomarkers and Interventions. University of Sydney, 2015-2016. C. Engeland (Co-I).

• NCBI Pubmed