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Greg Shearer
Gregory Shearer
Professor of Nutritional Sciences
Summary Statement

The consequences of over-nutrition and the stress of "western diets" related to lipid mediators and a global shift of dietary fatty acids; identifying markers of disease and better ways to prevent or manage disease.

Department
  • Nutritional Sciences - NUTR
  • Graduate Program
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Currently Accepting Graduate Students
Phone
Office Address
110 Chandlee Lab
University Park, PA 16802
Fax
814-863-6103
Professional Credentials

PhD

Grants and Research Projects

Lipid mediators are bioactive metabolites of dietary fatty acids. They act on tissues to alter many disease-related functions, including the stiffness of blood vessels and the body's response to stress.

Most investigations focus on the actions of individual lipid mediators, however over-nutrition and the stress of "western diets" is characterized by a global shift of dietary fatty acids, not a shift in any single fatty acid. The consequence of multiple changes in fatty acids is a corresponding change in the array of lipid mediators produced. We seek to understand disease-related functional changes in the context of globally changes and use them to identify markers of disease and better ways to prevent or manage disease.