Kim Wiersielis

Endocrine disrupting compounds and stress effects on cognition in mice.
Office: Room 034
Lab: Room 255
My research examines developmental exposure to endocrine disrupting compounds namely, organophosphate flame retardants and how they disrupt cognitive processing in the adult male and female offspring. In addition, it is well known that chronic stressful experiences can result in maladaptive affective states that impair learning and memory processes in both rodents and humans, often with a bias towards one particular sex. Thus, my central hypothesis is that perinatal organophosphate flame retardant exposure influences the developing cognitive and stress neurocircuitry, inducing long-lasting deficits in cognition and sensitize adults to chronic stress, with a greater impairment in one sex.